This is a total goals, aggregate score series; away goals are tiebreakers. Should both the aggregate and the away goals be tied at the end of a series, the higher seed will advance.
All times Eastern, home team listed first.
Playoffs – Liguilla – Semifinal First Legs
Thursday, May 18
Toluca (4) vs Chivas de Guadalajara (3) – 8:30 PM – Univision Deportes / UDN En Vivo / FuboTV
Tigres UANL (7) vs Tijuana (1) – 10:30 PM – Univision Deportes / UDN En Vivo / FuboTV