These games are single-elimination at the home of the higher seed. Should regulation end in a draw, the game will advance directly to penalty kicks (no extra time will be played).
All times Eastern, home team listed first.
Copa MX Round of 16 (Rescheduled)
Tuesday, October 24
Monarcas Morelia vs Tijuana – 8:00 PM – Univision Deportes / FuboTV
Toluca vs Atlante – 8:00 PM
América vs Cruz Azul – 10:00 PM – Univision Deportes / FuboTV
León vs Querétaro – 10:06 PM
Wednesday, October 25
Santos Laguna vs Necaxa – 8:00 PM – Univision Deportes / FuboTV
Pachuca vs Zacatepec – 8:06 PM
Monterrey vs Leones Negros – 9:30 PM – Galavision / FuboTV
Chivas de Guadalajara vs Atlas – 10:06 PM – Univision Deportes / FuboTV