The visitors started the game off well and they took the lead in the 12th minute. Juan Carrizo made the initial save, but the goalkeeper’s parry fell for Jonathan Rodríguez, who ran on to the loose ball and made it 0-1 for the Laguneros.
Monterrey quickly tied the game, however. In the 17th minute, John Stefan Medina got his head to a free kick and knotted the game up at 1-1.
After the equalizer, the Rayados began to dominate the game. Dorlan Pabón and Avilés Hurtado were particularly dangerous and Carlos Acevedo was kept busy in goal as he preserved parity.
But the hosts completed the turnaround in the 40th minute with another set piece, when Carlos Sánchez sent his free kick around the wall and into the net to give Monterrey the 2-1 lead going into halftime.
In the second half, Monterrey continued to dominate but struggled to find the goal that would put the game out of reach, while Santos was likewise thwarted in their search for an equalizer.
Then, in the 74th minute, substitute Jorge Benítez, who had just entered the game, received a good pass from Hurtado and gave Monterrey the insurance goal they’d been looking for: 3-1.
Then, in stoppage time, Hurtado drove into the box, one-on-one with the keeper; he couldn’t get a shot away but sent a backheeled pass to Carlos Sánchez, who finished off the play to make it 4-1.
With the 4-1 win, Monterrey advances to the semifinals while Santos is eliminated.