The semis are a total goals, aggregate score series; away goals are tiebreakers. Should both the aggregate and the away goals be tied at the end of a series, the higher seed will advance.
All times Eastern, home team listed first.
Playoffs – Liguilla – Semifinal First Legs
Wednesday, November 29
América (3) vs Tigres UANL (2) – 10:00 PM – Univision Deportes / FuboTV
Thursday, November 30
Monarcas Morelia (4) vs Monterrey (1) – 8:30 PM – Univision Deportes / FuboTV