The teams were paired up as follows, based on their seeding from the group stage:
Querétaro vs Santos Laguna
Cafetaleros vs Toluca
Pumas UNAM vs Necaxa
Zacatepec vs León
The quarterfinals are scheduled to be held between March 13th and 15th, with the exact dates and times of the four matches to be announced shortly.
Update: the schedule is as follows; all times Eastern, home team listed first.
Copa MX Quarterfinals
Tuesday, March 13
Zacatepec vs León – 9:06 PM
Santos Laguna vs Querétaro – 11:15 PM
Wednesday, March 14
Cafetaleros vs Toluca – 9:00 PM
Pumas UNAM vs Necaxa – 11:15 PM