The semifinals are a two-legged, home-and-away series decided by aggregate score. Away goals are tiebreakers; if both the aggregate and the away goals are level, the higher seed will advance.
All times Eastern, home team listed first.
Liguilla – Playoffs – Semifinal First Legs
Wednesday, December 5
Monterrey (5) vs Cruz Azul (1) – 9:00 PM – Fox Deportes
Thursday, December 6
Pumas UNAM (3) vs América (2) – 9:30 PM – Univision Deportes / FuboTV